I can reproduce this issue (no extensions other than those included in the Ubuntu session) in Ubuntu 18.10 and without the precondition in the bug report (I don't have auto-login and I can still reproduce this bug).
Andrea, does the following `journalctl -f` output help at all? https://paste.ubuntu.com/p/MWHpfHNh2K/ -- You received this bug notification because you are a member of Ubuntu Bugs, which is subscribed to Ubuntu. https://bugs.launchpad.net/bugs/1799293 Title: gnome session: Must ask twice to lock the screen To manage notifications about this bug go to: https://bugs.launchpad.net/ubuntu/+source/gnome-shell/+bug/1799293/+subscriptions -- ubuntu-bugs mailing list ubuntu-bugs@lists.ubuntu.com https://lists.ubuntu.com/mailman/listinfo/ubuntu-bugs