I have the same issue. Sometimes programs don't react on mouse clicks, but mouse cursor working. I have no idea how to reproduce the issue. But waiting a minute or so resolve the problem. At the same moment keyboard, left favorites menu and activities work fine.
Seems this is the issue of gnome-shell because it has high load at the moment of mouse locks. -- You received this bug notification because you are a member of Ubuntu Bugs, which is subscribed to Ubuntu. https://bugs.launchpad.net/bugs/1181666 Title: gnome-shell randomly blocks mouse clicks from working in app windows To manage notifications about this bug go to: https://bugs.launchpad.net/gnome-shell/+bug/1181666/+subscriptions -- ubuntu-bugs mailing list ubuntu-bugs@lists.ubuntu.com https://lists.ubuntu.com/mailman/listinfo/ubuntu-bugs