>From a replicate perspective:
 
This was on a EC2 t2.micro with AWS 21.2 Ubuntu Deep Learning AMI that is 
16.04, then installing nginx. The error only occurred when running a 
python+flask+uwsgi service.  e.g. a simple https/http server      

server {
    listen 443 ssl http2;
    listen [::]:443 ssl http2;
    listen 80;
    server_name SERVERNAME;
    ssl_certificate /etc/ssl/certs/mykey.crt;
    ssl_certificate_key /etc/ssl/private/mykey.key;
    ssl_protocols TLSv1.2 TLSv1.1 TLSv1;
    location / {
        include uwsgi_params;
        uwsgi_pass unix:/home/ubuntu/mywsgi_sock.sock;
    }
}

I haven't tried different releases though.

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https://bugs.launchpad.net/bugs/1581864

Title:
  nginx.service: Failed to read PID from file /run/nginx.pid: Invalid
  argument

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