Im using Ubuntu 20.04 LTS and have the same problem. I got the problem after 
upgrading from Kernel 5.4.0-73-generic to 5.4.0-74-generic. As I got in 
addition a firmware/microcode update it may be possible that the error is 
adjacent to that update too.
If I boot to kernel 5.4.0-73-generic I have access to the serial line (e.g. 
/dev/ttyACM3).

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https://bugs.launchpad.net/bugs/1931684

Title:
  cdc_acm: acm_port_activate - usb_submit_urb(ctrl irq) failed

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