The openbabel-perl API is quite good and used by quite a few people I
know. Right now, we all have to compile openbabel from sources instead
of using the deb package available in ubuntu. From sources, the
compilation of this binding is very easy : cd scripts/perl && perl
Makefile.PL && make && make test && make install (see
http://openbabel.org/wiki/Install_(source_code)#Install_the_Perl_bindings_globally
). I'm not familiar at all with the process of creating packages, but
I'm willing to help, if needed.

Aurélien.

-- 
python bindings not included
https://bugs.launchpad.net/bugs/125115
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