As it was suggested previously for some kind of logitech mouse you can try to 
restart this driver:
sudo modprobe -r hid_logitech && sudo modprobe hid_logitech

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You received this bug notification because you are a member of Ubuntu-X,
which is subscribed to xorg-server in Ubuntu.
https://bugs.launchpad.net/bugs/41301

Title:
  Mouse clicks stop working sporadically

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https://bugs.launchpad.net/ubuntu/+source/linux/+bug/41301/+subscriptions

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