I have the same issue on a new Asus Zenbook prime UX31A-R4003P. For me, it seems that the problem appears when I use VirtualBox. Suddenly, the mouse click does not work anymore on the laptop screen but it works on my external screen (HDMI one).
If I click <<Alt>> key as said by Andrey Sidorov, this solves the problem. -- You received this bug notification because you are a member of Ubuntu-X, which is subscribed to xserver-xorg-input-synaptics in Ubuntu. https://bugs.launchpad.net/bugs/1077805 Title: left click stops working after a while To manage notifications about this bug go to: https://bugs.launchpad.net/ubuntu/+source/xserver-xorg-input-synaptics/+bug/1077805/+subscriptions _______________________________________________ Mailing list: https://launchpad.net/~ubuntu-x-swat Post to : ubuntu-x-swat@lists.launchpad.net Unsubscribe : https://launchpad.net/~ubuntu-x-swat More help : https://help.launchpad.net/ListHelp