> I have 2 question:
> 1. Does HBase support scan data of rowkey by column?

You mean secondary indexes? No:
http://hbase.apache.org/book.html#secondary.indices

> 2. Which design is better? I think that design 2 is better when user have
> large amount of follower.

I cover a bunch of designs in this very recent thread:
http://search-hadoop.com/m/AXRdP1KKR5T1

J-D

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