System is running up-to-date Fedora 32. 

root@webster[3]->mailx  -v -v -s test ge...@hughes.net </dev/null
Null message body; hope that's ok
ge...@hughes.net... Connecting to [127.0.0.1] via relay...
ge...@hughes.net... Deferred: Connection refused by [127.0.0.1]

root@webster[6]->ping 127.0.0.1
PING 127.0.0.1 (127.0.0.1) 56(84) bytes of data.
64 bytes from 127.0.0.1: icmp_seq=1 ttl=64 time=0.080 ms
64 bytes from 127.0.0.1: icmp_seq=2 ttl=64 time=0.086 ms
64 bytes from 127.0.0.1: icmp_seq=3 ttl=64 time=0.091 ms
64 bytes from 127.0.0.1: icmp_seq=4 ttl=64 time=0.103 ms
^C
--- 127.0.0.1 ping statistics ---
4 packets transmitted, 4 received, 0% packet loss, time 3096ms
rtt min/avg/max/mdev = 0.080/0.090/0.103/0.008 ms

Suggestions for cause/diagnosis would be appreciated.
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