net::ERR_HTTP2_PROTOCOL_ERROR errors in version 10.1.29

[Thomas Hoffmann (Speed4Trade GmbH)]

Hello,
after upgrading from 10.1.25 to 10.1.29 I experience many 
net::ERR_HTTP2_PROTOCOL_ERROR in Edge and Chrome.
Firefox shows NS_ERROR_NET_RESET.
The website doesn't fully render.

Access-Log shows several HTTP 500 errors for static resources.
The other logfiles don't show any errors.

Does anybody observer the same issues?

My connector looks like:

                <Connector port="443" 
protocol="org.apache.coyote.http11.Http11NioProtocol"
               
sslImplementationName="org.apache.tomcat.util.net.openssl.OpenSSLImplementation"
               maxThreads="150" minSpareThreads="25"
               URIEncoding="UTF-8" useBodyEncodingForURI="false"
               enableLookups="false" disableUploadTimeout="true"
               acceptCount="100" scheme="https" secure="true"
               SSLEnabled="true"
               compression="force">
                <UpgradeProtocol 
className="org.apache.coyote.http2.Http2Protocol"  />
                <SSLHostConfig 
ciphers="ECDHE-ECDSA-AES128-GCM-SHA256:ECDHE-RSA-AES128-GCM-SHA256:ECDHE-ECDSA-AES256-GCM-SHA384:ECDHE-RSA-AES256-GCM-SHA384:ECDHE-ECDSA-CHACHA20-POLY1305:ECDHE-RSA-CHACHA20-POLY1305:DHE-RSA-AES128-GCM-SHA256:DHE-RSA-AES256-GCM-SHA384"
                                disableSessionTickets="true"
                                honorCipherOrder="false"
                                protocols="+TLSv1.2,+TLSv1.3">
                    <Certificate certificateKeyFile="\localhost.key"  
certificateFile="localhost.pem"   type="RSA"    />
                </SSLHostConfig>
    </Connector>


Thanks in advance!
Thomas