I had the same problem when installing web2py 2.19.1 on Mac OS X Catalina. I eventually solved the problem running the following code:
Annets-Mini:~ me$ export PATH=/usr/local/Cellar/postgresql/12.1/bin/:$PATH Annets-Mini:~ me$ export LDFLAGS="-L/usr/local/opt/readline/lib" Annets-Mini:~ me$ export CPPFLAGS="-I/usr/local/opt/readline/include" Annets-Mini:~ me$ export PKG_CONFIG_PATH="/usr/local/opt/readline/lib/pkgconfig" Annets-Mini:~ me$ export LIBRARY_PATH=$LIBRARY_PATH:/usr/local/opt/openssl/lib/ Annets-Mini:~ me$ pip install psycopg2 Collecting psycopg2 Using cached psycopg2-2.8.4.tar.gz (377 kB) Installing collected packages: psycopg2 Running setup.py install for psycopg2 ... done Successfully installed psycopg2-2.8.4 Annets-Mini:~ me$ Your using Linux but maybe this information points you in the right direction. Kind regards, Annet -- Resources: - http://web2py.com - http://web2py.com/book (Documentation) - http://github.com/web2py/web2py (Source code) - https://code.google.com/p/web2py/issues/list (Report Issues) --- You received this message because you are subscribed to the Google Groups "web2py-users" group. To unsubscribe from this group and stop receiving emails from it, send an email to web2py+unsubscr...@googlegroups.com. To view this discussion on the web visit https://groups.google.com/d/msgid/web2py/1246ad80-9788-499d-b9fc-68667766d176%40googlegroups.com.