Web2py is waiting for the first brave ONE to (be able to) GO and try to SCALE. I believe this person will get a lot of attention and resources from community and Massimo himself.
Real WORLD scalable implementations are VERY CUSTOM thing. like for example: http://python.mirocommunity.org/video/1886/djangocon-2010-scaling-the-wor btw, they use apache. My point is: let's focus on our killer products that will create good enough tracking and attention to.. scale.