Rob,

Here are some other causes I have seen for serious performance issues in
the past couple of years:

1) a bad cable or NIC connecting the web server with the database, or
the web server with the internet. This one made a huge difference. After
hours of time and lots of money spent by the customer on application
developers and network software integration specialists, somebody
thought to put some diagnostics on the NIC. It showed hundreds of
thousands of errors had occured (and caused retries) in the last few
hours. We replaced a $18 cable, and performance was great again.

2) anti-virus and/or anti-spyware software that was analyzing every byte
of data being transferred between the application server and the
database, looking for a possible trojan in the datastream. With Symantec
Corporate, we just had to exclude the database files from monitoring.
With the Beta of Microsoft anti-spyware, just last week, we couldn't
figure out how to exclude a file from inspection, so we just disabled MS
anti-spyware. It helped performance a lot.

Bill


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