Hi, I wanted to share that I successfully build Alien::wxWidgets on Mountain Lion with a freshly compiled Perl 5.16.0
I entered into the build directory for Alien::wxWidgets and launched following Build.PL command: perl Build.PL --wxWidgets-extraflags="--with-macosx-sdk=/Applications/Xcode.app/Contents/Developer/Platforms/MacOSX.platform/Developer/SDKs/MacOSX10.8.sdk --with-macosx-version-min=10.6" --wxWidgets-build='yes' --wxWidgets-source='tar.bz2' --wxWidgets-version=2.9.3 Hope this helps other people.. best -- erik