Hello Krish--

> 
> I am interested in refining a structure of a small protein DMSO
> using the implicit solvent approach. First of all, will it be a
> valid approach to adopt the examples shown in the tutorial
> section. In that case, how would one adjust the dielectric constant
> for DMSO? Thanks for the help.
> 

That's an interesting question to which I don't have an immediate
answer. Certainly, different parameters would be needed to model
DMSO. The question is do those parameters already exist. You might try
googling EEF1 and DMSO. After a very brief search I came up empty.

Anyone who knows of implicit solvent models used with non-water
solvent might speak up.

best regards--
Charles
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