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Hello Michael--

> Thanks for your reply to my message. I just wanted to check if there
> is a step two for your answer to my first question. I guess it would
> be to read in the MTSL coordinates? Could you also point me at the
> sections of the manual that explain how to assign semi-random
> coordinates and regularize coordinates since I am new to Xplor and
> have to learn what is meant by these terms and couldn't see them in
> the index. 

genExtendedStructure is documented here:
http://nmr.cit.nih.gov/xplor-nih/doc/current/python/ref/protocol.html


>     Does regularize mean to combine the good crystal
> coordinates with the new MTSL coordinates extracted from the extended
> structure? Would the number of the MTSL residue also be taken from the
> extended structure containing the MTSL?

by regularize I mean to fix up covalent bonds, angles and improper
torsions - so that the proper structure can be determined by changing
torsion angles only.

if you use 
procol.genExtendedStructure(sel="not known")
then coordinates not already read in are assigned random values and then
regularized. 

The MTSL-derivatized residue's number should be the same as the number
of the underivatized version.

regards--
Charles
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