Hello Tom--

> Hi, is there a way of optimizing an alignment tensor during a
> RDC-restrained dynamics calculation in XPLOR?\xa0\xa0\xa0 In AMBER,
> the tensor components are iteratively optimized for best fit with
> experimental RDC values.
> 

The standard procedure (in e.g. eginput/gb1_rdc/refine.py) is to
optimize the tensor components during structure calculation. This is
covered in some detail in

   G.A. Bermejo and C.D. Schwieters, ``Protein Structure Elucidation 
   from NMR Data with the Program Xplor-NIH,'' Methods Mol Biol. 1688,
   311-340 (2018)

Charles

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