Hi Lucas,

N-terminal acetylation is specified in the sequence itself by adding ACE as the 
first residue.

Best,

Guillermo



Hello,

I use Xplor-NIH for calculations of peptides that are normally 
C-terminus-amidated and have been using the -amidate_cterm option for the 
seq2psf script without issue. The question that I have is whether such an easy 
function exists to insert an acyl group at the N-terminus of a given peptide 
and, if such an easy solution does not exist, what workaround can I use in 
order to introduce this acyl group in Xplor-NIH calculation?

Best regards,

--
Lucas Raposo Carvalho
BSc in Chemistry by Federal University of Itajubá (UNIFEI)
MSc in Chemistry by Federal University of Itajubá (UNIFEI)
PhD candidate in Chemistry by Federal University of Minas Gerais (UFMG)
Contact: +55 (12) 9 9223-6378

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  • N-terminus acylation Lucas Raposo Carvalho
    • Re: N-terminus acylation Bermejo, Guillermo (NIH/NIDDK) [E]

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