Hello Mark--

> 
> we would like to calculate a structure of a protein where a Cu atom
> is bound to histidine residues. Can you tell us how to set-up the
> histidine patches for Cu? I have done this before for Zn in CNS. 

In Xplor-NIH's toppar subdirectory there is dihiscu.top/par which
contains a patch (and parameters) for ligating two histidines to
Cu(II) via the NE2 atom. This might be modified if there are a
different number of ligated histidines. Please let us know if you need
assistance with this.

best regards--
Charles

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