Leonid > The original question was whether it is beneficial to add > adult data to the pediatric (in the specific case under > study). Your previous e-mail could be interpreted as the > suggestion that one can estimate model parameters with the > pediatric data alone if the pediatric study design is > optimal.
My previous email was more aimed at the comments about having fewer observations than parameters to estimate. > I think one should use both datasets together (in > the specific case that was described) and it looks like we > are in agreement on this point. Yes we are. Steve --