[Sudhir R]      Doctor with a heart 

In conversation with Prof. Falcinelli who pioneered the technique of using a 
tooth to nurture the eye. 

Caring touch: Prof. Falcinelli. 
An eye for an eye will only make the whole world blind, said Mahatma Gandhi in 
a non-medical context. But a tooth to nurture 

an eye can actually give vision. Thanks to MOOKP - Modified Osteo Odonto kerato 
prosthesis (osteo (bone), odonto 

(tooth), keratoprosthesis (artificial cornea) - pioneered by Italian surgeon 
Prof. Giancarlo Falcinelli, Chief Ophthalmologist 

Emeritus S. Camillo Hospital and Scientific Director of the Osteo Odonto 
Keratoprosthesis Foundation, there is new hope for 

corneal blindness (there are 10 million across the world and India accounts for 
4.6 million).

MOOKP, in which a person's own tooth is used as biological tissue to integrate 
a plastic cornea with the eye, comes as a boon 

for patients with severe dry eyes and ocular damage in whom conventional 
corneal transplants are of no help.

Prof. Falcinelli trained a team of surgeons at the Sankara Nethralaya, Chennai, 
led by the late Dr. G. Sitalakshmi who he recalls 

possessed excellent surgical skills and operated with great confidence and 
intelligence and successfully restored sight to 33 

patients. Prof. Falcinelli was in Chennai recently to launch India's first 
MOOKP training programme at Sankara Nethralaya. 

The technique 
Compassionate and caring, the 84-year-old surgeon is a doctor with a heart. 
Borrowing the original technique from his mentor 

Prof. Strampelli, Prof Falcinelli made several refinements, simplifying and 
perfecting the technique to provide clearer vision for 

the patient and ensure longer life for the prosthesis.

"What we are putting in is an artificial cornea because the original is 
irreparably damaged due to trauma, accidents, chemical 

injuries, Steven Johnson's syndrome (severe allergy to medication) or other 
immune disorders. Before MOOKP, all our efforts 

to provide an artificial cornea without the support of a biocompatible tissue 
were desperate attempts" says Prof Falcinelli 

What does it take for a surgeon to be able to perform MOOKP? "MOOKP requires 
tremendous patience because it's a long 

procedure and necessitates a lot of interaction with the patient. Whoever does 
MOOKP takes on a great responsibility since it's 

a little known procedure and, after the surgery, patients have to necessarily 
come back to the same surgeon."

Interest in the eye 
Ask Prof. Falcinelli how he got interested in the eye and he turns emotional. 
Peppino, a childhood friend, wanted to keep his 

hands warm in winter. So he devised a contraption: a container that had lime in 
it with water dripping from another source. 

Unfortunately too much water got in and the mixture splashed on his face 
resulting in loss of vision. 

This inspired Prof. Falcinelli to become an eye surgeon. He travelled across 
the world studying artificial corneas. After years of 

perfecting the MOOKP he operated on Peppino and gave him the gift of sight . 

As for the advances we can expect in the future, he says the first is economic. 
"This is not a one shot operation. The procedure 

consists of at least two stages, each of four to five hours duration. It is 
expensive because of the time spent by the surgeons and 

the support staff the hospital needs to dedicate. In the time required to do 
MOOKP many other corneal surgeries can be done." 

Though corneal blindness is not peculiar to poor countries, he is pained that 
he hasn't been able to take this procedure to some 

affluent countries because insurance companies are not ready to pay.

Other patients 
Prof. Falcinelli is also concerned that quite a few patients who come for the 
MOOKP procedure also suffer from glaucoma. "It 

would be a tragedy if patients who regained vision due to MOOKP had to lose it 
to glaucoma. In such cases I have devised two 

procedures, which helps 80 per cent of the patients get over the problem. For 
the remainder, a cure must be found. Looking at 

the skill and the dedication of my Indian colleagues, I am hopeful of finding a 
solution with their support," he says by way of a 

tribute .

* * * 

About MOOKP 
Stage 1A is the initial stage to examine the inside of the eye and to assess 
the status of the retina and the optic nerve, which have 

to be healthy for good results. Stage 1B involves removal of the mucous 
membrane from the inside of the cheek and placing it 

on the surface of the eye (most cases of corneal blindness have extremely dry 
eyes). Simultaneously a canine tooth is extracted 

with the surrounding bone and root, a hole is drilled and the plastic cylinder 
(plastic cornea) made of the same material as an 

intraocular lens used after cataract surgery is fixed and the prosthesis is 
placed under the skin of the cheek, just below the eye to 

enable it to develop a soft tissue covering. 

In the final stage the prosthesis is removed from the cheek and implanted in 
the eye such that there is a clear optical cylinder. 

Good vision is achieved within a week.

The entire procedure from start to finish takes six months with a few days of 
hospitalisation at each stage and costs Rs. 

1,60,000. At Sankara Nethralaya MOOKP is done free of cost for patients who 
cannot afford the treatment.

This information available at 
http://www.hindu.com/mag/2007/11/25/stories/2007112550140500.htm 
 
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