Does the Mikrotik DNS cache listen on both TCP and UDP port 53?  In
past I always dropped both in input chain on the pppoe interface but I
am not sure it actually listens on the TCP port?

> Assuming you have DNS set to Allow Remote Requests (which must be on for
> local customers to use the Mikrotik as their DNS server), make sure you have
> an Input chain rule to drop UDP and TCP destination port 53 on the WAN
> interface.  Mikrotik’s QuickSet leaves the router open to DNS amplification
> attacks.
>
> Also check if you have NTP server enabled, that’s another amplification
> attack method.
>

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