From my log:

Jan 18 14:01:35 mail amavis[23844]: (23844-03) ESMTP::10025 
/var/amavis/amavis-20110118T140128-23844-f7tP1VEM:
<t...@vds28.bmt-gbr.de> -> <eurap.germ...@charite.de> SIZE=4461
Received: from mail.charite.de ([127.0.0.1]) by localhost
(mail.charite.de [127.0.0.1]) (amavisd-new, port 10025) with ESMTP for
<eurap.germ...@charite.de>; Tue, 18 Jan 2011 14:01:35 +0100 (CET)
Jan 18 14:01:35 mail amavis[23844]: (23844-03) Checking: 8CD6ny0L_CHt
[212.48.120.20] <t...@vds28.bmt-gbr.de> -> <eurap.germ...@charite.de>
Jan 18 14:01:35 mail amavis[23844]: (23844-03) p001 1 Content-Type:
text/html, size: 3881 B, name: 
Jan 18 14:01:35 mail amavis[23844]: (23844-03) Negative SMTP response
to data-dot (<eurap.germ...@charite.de>): 550 5.7.1 ph27\n5.7.1
Contact postmas...@charite.de for assistance
Jan 18 14:01:35 mail amavis[23844]: (23844-03) (!)FWD from
<t...@vds28.bmt-gbr.de> -> <eurap.germ...@charite.de>,BODY=7BIT 550
5.7.1 from MTA(smtp:[127.0.0.1]:10026): 550 5.7.1 ph27\n5.7.1 Contact
postmas...@charite.de for assistance
Jan 18 14:01:35 mail amavis[23844]: (23844-03) (!!)TROUBLE in
check_mail, but must continue (1): delivery-notification FAILED:
Assert failed: 0, 1, 0 at /usr/sbin/amavisd line 9223, <GEN17> line
2810.
Jan 18 14:01:35 mail amavis[23844]: (23844-03) (!!)TROUBLE in
process_request: wrap_smtp_resp: bad SMTP response code: '' at
/usr/sbin/amavisd line 4582, <GEN17> line 2810.
Jan 18 14:01:35 mail amavis[23844]: (23844-03) (!)Requesting process
rundown after fatal error
Jan 18 14:01:35 mail amavis[23844]: (23844-03) (!)TempDir removal:
tempdir is to be PRESERVED:
/var/amavis/amavis-20110118T140128-23844-f7tP1VEM
Jan 18 14:01:35 mail amavis[23844]: (23844-03) smtp session rundown
all sessions, idle 0.0 s, smtp:[127.0.0.1]:10026, state ehlo
Jan 18 14:01:35 mail amavis[23844]: (23844-03) smtp session rundown,
sending QUIT
Jan 18 14:01:35 mail amavis[23844]: (23844-03) smtp session rundown,
closing session smtp:[127.0.0.1]:10026

My recent main.cf change:
smtpd_reject_footer = Contact postmas...@charite.de for assistance
seems to be the culprit!

-- 
Ralf Hildebrandt
  Geschäftsbereich IT | Abteilung Netzwerk
  Charité - Universitätsmedizin Berlin
  Campus Benjamin Franklin
  Hindenburgdamm 30 | D-12203 Berlin
  Tel. +49 30 450 570 155 | Fax: +49 30 450 570 962
  ralf.hildebra...@charite.de | http://www.charite.de
            

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