On Mon, Jan 6, 2014 at 1:34 AM, Hans-Ulrich
<hans-ulrich.kl...@uni-muenster.de> wrote:
> Hi Hernik,
>
> Clearing the cache as you suggested did the trick:
>
>
>> clearCache(dirs="aroma.affymetrix", recursive=TRUE, prompt=FALSE)
>
> Calculation of the sets of pobes with common SNP nucleotide pairs took much
> more time after clearing the cache and I finally got 6 groups + "missing" as
> expected. There must have been some corrupt files in my cache.

Thanks for the follow up.  I don't know how the *contents* of those
cache files got corrupted (the files themselves were valid since that
corrupt content got read in).  I have never seen this before, but my
best guess is that the ACS file was corrupt, an I/O error occured
while parsing that, and/or you somehow got used a non-working version
of the affxparser package.

The reason for it being slow is that it had to reparse and rebuild the
CDF structure and lots of other things, which are now saved in file
cache and for quick access.  The clearCache() call erased all of the
aroma.affymetrix file cache, so you'll find that it needs to rebuild
the cache also for other chip type - I though that was the safest
thing to do.

Cheers,

Henrik

>
> Thanks again for your help!
>
> Best,
> Hans-Ulrich
>
>
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When reporting problems on aroma.affymetrix, make sure 1) to run the latest 
version of the package, 2) to report the output of sessionInfo() and 
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