Re: slay the spire now accessible!
You mean "slimed"?
It's a debuff your enemy puts on you, as far as I know it is shuffled into your draw pile and if you draw it, you can destroy it if you pay the energy cost, otherwise it'll just keep coming up.
You can look at it this way: If you draw a slime card in a round, that means you have drawn one less card, because it is useless to you.
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