Hi Michael, I have a use case that is similar to https://support.bioconductor.org/p/81267/#82142 and looks to me like it might need some changes in rtracklayer to work. That's why I'm posting it here this time.
Basically, I'm trying to use rtracklayer to import a bigwig file over the web which is in a different type of url than before. Using utils::download.file() with the defaults doesn't work, I have to use method = 'curl' and extra = '-L'. More specifically, the original url http://duffel.rail.bio/recount/DRP000366/bw/DRR000897.bw has an effective url https://content-na.drive.amazonaws.com/cdproxy/templink/i_aQAPZJkJ9d9lN1NO5DJJtlbpvAdgbNuc1SkqSTHFouFiZq5 Now, using the second url with utils::download.file() and default methods also doesn't work. It does on the browser though. As you can see, downloading the file doesn't work out of the box. Which I guess that it's not surprising that using rtracklayer I get errors like: In seqinfo(ranges) : No openssl available in netConnectHttps for content-na.drive.amazonaws.com : 443 You can find further details (code and log file) at https://gist.github.com/lcolladotor/c500dd79d49aed1ef33ade5417111453 Thanks, Leo _______________________________________________ Bioc-devel@r-project.org mailing list https://stat.ethz.ch/mailman/listinfo/bioc-devel
