Leon,

On Dec 9, 2006, at 7:59 AM, Leon Deouell wrote:

Thanks again for your help. I am making nice progress. My questions now are: 1. Is it possible to see the foci on volume slices? It seems I can only see
them on surface files.

Yes - Use File: Open Data File: Open Foci File - Volumes (*.foci). This will open any valid foci file, and use whatever foci color file you have selected.

Then select Display Control: Page Selection: Foci and toggle Show Volume Foci on.

2. Regardless of foci, when I switch to 'oblique' in a window displaying a volume, I loose the yoking option - clicking on the surface does not change the display in the volume window and vice versa. Is there a way to tilt the
volume and remain "yoked"?

My observations: Clicking on the surface does not move the cursor in the volume when viewing oblique slices, but it works for me in the reverse direction - clicking on the volume slice does highlight the corresponding node in the surface.

Getting it to go in the reverse direction would be useful. Also, I just noticed that the surface slices don't display in the oblique volume slices even when selected using the O/L-Volume: Surface Outline option. However, John Harwell has a fair amount on his platter right now, so I'm not sure when he'll be able to get to it.

David VE


Leon

-----Original Message-----
From: [EMAIL PROTECTED]
[mailto:[EMAIL PROTECTED] On Behalf Of Donna Dierker
Sent: Friday, December 08, 2006 7:49 PM
To: Caret, SureFit, and SuMS software users
Subject: Re: [caret-users] using caret for a meta-analysis

On 12/08/2006 11:44 AM, Leon Deouell wrote:
Dear Donna,

Thanks for the information. I realize the issue of different coordinate spaces. What I am not sure of is this: If I specify the original space (e.g., T88 or SPM2) for each study in the foci text file, or in the study tab when entering individual foci using the GUI (5.2.2 in the tutorial), will Caret take this into consideration when projecting to the PALS brain?

Yes
Or do I have to go through some intermediate of transforming from one
space
to another? Originally I was considering using the tal2mni Matlab function from the Cambridge imagers web site you mentioned to get all coordinates
into MNI space, but maybe this is redundant in Caret.

The idea is to make this unnecessary -- as long as the stereotaxic space
in question is well-represented by one of these:

711-2C
AFNI
FLIRT
MRITOTAL
SPM2
SPM95
SPM96
SPM99
Thanks,

Leon

-----Original Message-----
From: [EMAIL PROTECTED]
[mailto:[EMAIL PROTECTED] On Behalf Of Donna Dierker
Sent: Friday, December 08, 2006 6:34 PM
To: Caret, SureFit, and SuMS software users
Subject: Re: [caret-users] using caret for a meta-analysis

Hi Leon,

Shawn has done exactly what you want to do, so if anyone knows the
pitfalls, he does. ;-)

Besides Shawn's useful notes, make sure you read sections 1.2.3 and 5.2
of this tutorial, if you haven't done so already:

CARET_TUTORIAL_SEPT-06
http://sumsdb.wustl.edu:8081/sums/directory.do?id=6585200

This tutorial includes a spec file intended for this purpose. The ones in the Caret fmri_mapping directory are not really intended for use as
"visualization" specs; rather, Caret uses them when mapping fMRI data
onto PALS_B12. You can, however, use the average fiducial surfaces in
that directory for your foci-related purposes. Note that studies report results in stereotactic spaces other than MNI (e.g., AFNI users report true Talairach-Tournoux (T88) coordinates, which differs significantly from MNI -- see http://imaging.mrc-cbu.cam.ac.uk/imaging/ MniTalairach; wustl.edu researchers typically use "711-2*" space -- somewhere between
T88 and MNI). See
http://brainvis.wustl.edu/help/pals_volume_normalization/ for additional
details.

Reading tutorial section 5.2 may clarify some of this, but you're likely
to have residual questions/confusion about these spaces.

On 12/08/2006 10:24 AM, Christ, Shawn E. wrote:

Hi Leon,

I have been working with David, Donna, and John on utilizing Caret for
precisely this purpose with respect to an ALE-type meta-analysis on
deception that we have submitted for publication. You can download a
copy of our spec file, etc. at
http://sumsdb.wustl.edu:8081/sums/directory.do?id=6600996

I've also uploaded a copy of my personal notes on how to transform
foci using Caret. They can be found at
http://www.shawnchrist.com/FociTransform.pdf

I hope this helps!

Best,

-Shawn

--------------------------

Shawn Christ, Ph.D.

Assistant Professor

Department of Psychological Sciences

University of Missouri-Columbia

210 McAlester Hall

Columbia, MO 65211

[EMAIL PROTECTED] <mailto:[EMAIL PROTECTED]>

-------------------------------------------------------------------- ----

*From:* [EMAIL PROTECTED]
[mailto:[EMAIL PROTECTED] *On Behalf Of *Leon
Deouell
*Sent:* Friday, December 08, 2006 9:50 AM
*To:* caret-users@brainvis.wustl.edu
*Subject:* [caret-users] using caret for a meta-analysis

Hi,

I am in the process of doing a meta-analysis of imaging data. I am a
complete novice to Caret, but from a quick look it seems it's
stereotaxic foci functions would be ideal to log the peak activity
data from different studies. Eventually I would like to display
symbols for each peak on a 3D brain rendering of some sort. Perhaps
Naively, I thought I could load a template brain (open a spec file),
add foci (assuming for a moment I have all coordinates in MNI space)
using for example 'layers>foci>map stererotaxic focus', and see them
pop-out on the brain. However, at first pass, I run into the following
questions:

a) What brain (spec file) should I load from the fMRI_mapping folder?
There are so many of them. Is there anywhere a text file describing
what these different files are?

b) If I enter a focus with coordinates which happen to be under the
surface by a few millimeters, they don't show up on the surface. Is
there a way to project them to the surface or to make the brain
'transparent'?

c) Once I have the foci entered, can I project them to an inflated
brain, and if so, how?

Finally, I assume I am not the first to want to use Caret for this
purpose - does someone have a 'recipe' for such a project or tips on
what pitfalls to avoid?

Thanks,

Leon

----------------------------------------------------

Dr. Leon Y Deouell, MD, PhD

Department of Psychology

The Hebrew University of Jerusalem

Jerusalem 91905

Israel

Tel: +972-2-5881739

Fax: +972-2-5825659

http://pissaro.soc.huji.ac.il/~leon/Lab
<http://pissaro.soc.huji.ac.il/%7Eleon/Lab>

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--
Donna L. Dierker
(Formerly Donna Hanlon; no change in marital status -- see
http://home.att.net/~donna.hanlon for details.)

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