*** For details on how to be removed from this list visit the ***
*** CCP4 home page http://www.ccp4.ac.uk ***
Alex McPherson asked me to post this for him.
TO THE COMMUNITY:
I would like to thank all of you who responded to my request to
contribute any observations of “mysterious density” and what you
believed or knew it to be. Below is the current collection.
Best to all,
Alex McPherson
Mysterious Small Molecules Observed in Crystals by the Community
Buffers:
acetate, cacodylate,
MOPS, HEPES,
MES, TRIS,
CHES
Reducing Agents:
DTT, mono thiol glycerol, BME
Precipitants:
sulfate, PEG 400,
dioxane, heptaethylene glycol,
MPD, tetraethylene glycol,
phosphate, hexanediol,
jeffamine
Cryogens:
MPD, ethylene glycol,
glycerol, mannitol
Ions:
sulfate, phosphate,
arsenate, magnesium,
cadmium, calcium,
sodium, iodide,
chloride, bromide
Lipids and Detergents:
several reports, molecules largely not identified
Other Molecules:
benzoate, acetyl mannose,
benzamidine, formate,
guanosine, lipopolysaccharide,
dipeptide, phenyl-hexane,
peptide, amino acid,
NADP, sarcosine,
nucleic acid, colored dyes,
phenol, oligonucleotides,
disaccharide, tartrate,
non covalently bound heavy atom cmpds.
