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Sorry I'm late, What about malic acid (from apples) in the reservoir? Solid malic acid has a nice smell, so maybe malic acid in the reservoir would slowly acidify the drop, at least much slower than a very volatile acid such as acetic. -Dan On Mon, 4 Dec 2006, Andrew Wong wrote: > *** For details on how to be removed from this list visit the *** > *** CCP4 home page http://www.ccp4.ac.uk *** > > > Hi > > Just a quick question.. for doign hanging drop, is there anyway that we > can decrease the pH of the drops on a (somewhat) controlled way, say over > a period of couple of weeks? Thanks > > > Andrew >