A post-doctoral position is available to study the structure and
function of large catalytic RNA molecules. The work is a combination of
crystallographic, biochemical, and biophysical work and is focused
primarily on understanding the structure and mechanism of RNase P.
Strong previous experience with RNA work and/or crystallography of
macromolecules is highly desirable.
Our laboratory is located at Northwestern University in Evanston,
Illinois, in the shores of Lake Michigan and just outside of Chicago. We
have outstanding in-house facilities for all aspects of the work and
also easy access to the Advanced Photon Source at Argonne National
Laboratory, just 30 miles away.
Please submit inquiries to Alfonso Mondragón
([EMAIL PROTECTED]) attaching a copy of your CV and the name
of three references.
For references to our work in this area, see:
• Krasilnikov AS, Yang X, Pan T, Mondragón A. 2003. Crystal structure
of the specificity domain of ribonuclease P., Nature, 421. 760-764, 2003.
• Krasilnikov, A.S. and Mondragón, A. On the occurrence of the T-loop
RNA folding motif in large RNA molecules. RNA, 9, 640-643, 2003.
• Krasilnikov, A.S., Xiao,Y., Pan,T. and Mondragón,A. Basis for
Structural Diversity in Homologous RNAs, Science, 306, 104-107, 2004.
• Torres-Larios A., Swinger K. K., Krasilnikov A. S., Pan T., Mondragón
A. Crystal structure of the RNA component of bacterial ribonuclease P.
Nature. 437, 584-587, 2005.
• Torres-Larios A., Swinger K. K., Pan T., Mondragón A. Structure of
ribonuclease P - a universal ribozyme. Curr. Opin. Struct. Biol. 16,
327-335, 2006.
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Alfonso Mondragón
Department of Biochemistry, Molecular Biology and Cell Biology
Northwestern University
2205 Tech Drive
Evanston, IL 60208-3500
Tel. (847)491-7726
Fax. (847)467-6489
Email: [EMAIL PROTECTED]
