And I apologize for being crabby about it. I realize its hard for people from different traditions and different native tongues to figure out the best way to start an English letter to people you've never met.
---- Original message ---- >Date: Fri, 21 Aug 2009 16:50:28 -0000 >From: Debajyoti Dutta <debajyoti_dutt...@rediffmail.com> >Subject: [ccp4bb] I apologize >To: CCP4BB@JISCMAIL.AC.UK > > Hi everybody, > > I really apologize to every members of CCP4BB for > not to give attention to my addressing phrase. It is > truly misleading. I swear not to make such bad > mistake in future. I am really ashamed for such a > deed. > > Sincerely > Debajyoti Dutta > > On Fri, 21 Aug 2009 21:29:23 +0530 wrote > >Dear Sir, > Please don't assume that all crystallographers are > male. > > ---- Original message ---- > >Date: Thu, 20 Aug 2009 16:45:55 -0000 > >From: Debajyoti Dutta > <debajyoti_dutt...@rediffmail.com> > >Subject: Re: [ccp4bb] cyseteine modification > >To: CCP4BB@JISCMAIL.AC.UK > > > > Dear Sir, > > > > Thank you all who have replied. I jast want to > > enquire that if there is any option in coot to > > introduce the OH bond with Cys residue as well as > to > > introduce the secondary peptide like bond between > > carboxylic carbon with amino group of lys. > > > > Sincerely > > Debajyoti Dutta > > > > On Wed, 19 Aug 2009 20:58:44 +0530 wrote > > > > > > > Dear Debajyoti > > > > There is also the sulfenic acid species (-S-OH) > > which is actually > > the first oxidized form of sulfhydryls on the way > to > > sulfonic acid. However > > sulfenic acids are very susceptible to further > > oxidation to sulfinic and sulphonic > > acids, and therefore need a protective chemical > > environment to remain stable. > > > > See for example some previous work of ours on > > sulfenic and > > sulfinic forms of active-site cysteines in > > glutathione reductase (Nature > > Structure Biology vol 5, 267-271, 1998) and the > > corrresponding pdb entries 1dnc > > and 1gsn. > > > > Best regards > > > > Savvas > > > > ---- > > Savvas Savvides > > L-ProBE, Unit for Structural Biology > > Ghent University > > K.L. Ledeganckstraat 35 > > 9000 Ghent, BELGIUM > > office: +32-(0)9-264.51.24 ;mobile: > > +32-(0)472-92.85.19 > > Email: savvas.savvi...@ugent.be > > http://www.lprobe.ugent.be/xray.html > > > > From: CCP4 bulletin board > > [mailto:ccp...@jiscmail.ac.uk] On Behalf Of > > Debajyoti Dutta > > Sent: Wednesday, August 19, 2009 4:42 PM > > To: CCP4BB@JISCMAIL.AC.UK > > Subject: [ccp4bb] cyseteine modification > > > > Dear Sir, > > > > Is there any other oxidation states of cysteine > > other than cysteine sulphinic > > acid and cysteine sulphonic acid. In my protein, > the > > cysteine molecule is > > definitely overoxidized but the electron density > is > > not corresponding to the > > sulphinic or the sulphonic acid. The positive > > density looks as if it can > > accomodate only one oxygen atom and not more. > > > > Thank you for reply in advance. > > > > Sincerely > > Debajyoti Dutta > > > > > > > >E-mail message checked by Spyware Doctor > > (6.1.0.447)Database version: > > > 6.13080http://www.pctools.com/spyware-doctor-antivirus/ > > > > [IMG] > Phoebe A. Rice > Assoc. Prof., Dept. of Biochemistry & Molecular > Biology > The University of Chicago > phone 773 834 1723 > http://bmb.bsd.uchicago.edu/Faculty_and_Research/01_Faculty/01_Faculty_Alphabetically.php?faculty_id=123 > > RNA is really nifty > DNA is over fifty > We have put them > both in one book > Please do take a > really good look > http://www.rsc.org/shop/books/2008/9780854042722.asp > > [IMG] Phoebe A. Rice Assoc. Prof., Dept. of Biochemistry & Molecular Biology The University of Chicago phone 773 834 1723 http://bmb.bsd.uchicago.edu/Faculty_and_Research/01_Faculty/01_Faculty_Alphabetically.php?faculty_id=123 RNA is really nifty DNA is over fifty We have put them both in one book Please do take a really good look http://www.rsc.org/shop/books/2008/9780854042722.asp
