If you want to merge them into a single dataset, you need to go back to the unmerged intensities (ie the output of eg Mosflm), combine them together, best done with Pointless (ccp4i task "Find or match Laue group") and scale them together in eg Scala (task "Scale and merge intensities" )
Phil On 30 Sep 2010, at 08:03, jai mohan wrote: > Dear all crystallographers, > > Recently I have collected two data sets from two different crystals, first > data at 2.6A and second is at 1.9A, the datasets were isomorphous. I tried to > merge the two dataset as a single MTZ file using CAD (CCP4i), but it is > unsuccessful, i hope that the error starts from the column label of the data > sets. The first data has 13 and second data has 18 columns. Please guide me > how do i select the column labels. Need all of your valuable suggestion and > advice. > > regards > > Jai > >