This is regarding Ethan´s point, particularly:
  >2) the protein has crystallized as a monomer even though it
  >[sometimes] exists in solution as a dimer.  The interface
  >seen in the crystal is not the "real" dimer interface and
  >thus the PISA score is correct.
I see the same exact interface in a crystal of a close homologue that belongs 
to a different space group (hexagonal vs tetragonal system)

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