On 10/11/2011 12:33 PM, Garib N Murshudov wrote:
We need better way of estimating "unobserved" reflections.
Indeed we do! Because this appears to be the sum total of how the correctness of the structure is judged. It is easy to forget I think that from the "point of view" of the refinement program, all reflections flagged as belonging to the "free" set are, in effect, "missing". So Rfree is really just a score for how well DFc agrees with Fobs?
-James Holton MAD Scientist
