On 19/10/11 9:19 PM, "eugene.krissi...@stfc.ac.uk" <eugene.krissi...@stfc.ac.uk> wrote:
>In case when ASU has the same multiplicity (number of chains) as the >probable biological assembly, the latter is an ASU as well. In such a >case, the PDB suggests to choose ASU in the form of that assembly, purely >for simplicity. It seems to me that this is not an unreasonable >suggestion and it would be nice if that were a common practice. Maybe I am misunderstanding what you are saying Eugene, but the ASU interface may not necessarily be the biological interface. I think it is perfectly possible that two subunits in a biological dimer, for example, may be related by crystallographic axis, but the NCS may be a different non-physiological crystal contact, therefore the ASU won't be the same as the biological dimer. So I am not sure if the above applies in general. Bostjan Bostjan Kobe NHMRC Research Fellow Professor of Structural Biology School of Chemistry and Molecular Biosciences and Institute for Molecular Bioscience (Division of Chemistry and Structural Biology) and Centre for Infectious Disease Research Cooper Road University of Queensland Brisbane, Queensland 4072 Australia Phone: +61 7 3365 2132 Fax: +61 7 3365 4699 E-mail: b.k...@uq.edu.au URL: http://www.scmb.uq.edu.au/staff/bostjan-kobe Office: Building 76 Room 329 Notice: If you receive this e-mail by mistake, please notify me, and do not make any use of its contents. I do not waive any privilege, confidentiality or copyright associated with it. Unless stated otherwise, this e-mail represents only the views of the Sender and not the views of The University of Queensland. >
