Re: [ccp4bb] an ambiguous result of molecular replacement

[Leonid Sazanov]

Hi, we had the same case in apparent C2221, with many similarly shifted Phaser 
solutions with high scores. The reason was that crystals were actually nearly 
perfectly twinned in P21, so indexing and processing indicated C2221. Once data 
was re-processed in P21, Phaser could easily find two distinct solutions - one 
for each of twin domains, with LLG scores roughly reflecting twin ratios. 
Similar case is discussed in detail here:
http://www.ncbi.nlm.nih.gov/pubmed/15039553