Hi Leonid,

Thank you for your valuable suggestion. It is exactly the case. When I
tried P21, it works well. The solution is now very clear.

Best,
Zhiyi

On 3/31/12, Leonid Sazanov <saza...@mrc-mbu.cam.ac.uk> wrote:
> Hi, we had the same case in apparent C2221, with many similarly shifted
> Phaser solutions with high scores. The reason was that crystals were
> actually nearly perfectly twinned in P21, so indexing and processing
> indicated C2221. Once data was re-processed in P21, Phaser could easily find
> two distinct solutions - one for each of twin domains, with LLG scores
> roughly reflecting twin ratios.
> Similar case is discussed in detail here:
> http://www.ncbi.nlm.nih.gov/pubmed/15039553
>
>

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