Hi Leonid, Thank you for your valuable suggestion. It is exactly the case. When I tried P21, it works well. The solution is now very clear.
Best, Zhiyi On 3/31/12, Leonid Sazanov <saza...@mrc-mbu.cam.ac.uk> wrote: > Hi, we had the same case in apparent C2221, with many similarly shifted > Phaser solutions with high scores. The reason was that crystals were > actually nearly perfectly twinned in P21, so indexing and processing > indicated C2221. Once data was re-processed in P21, Phaser could easily find > two distinct solutions - one for each of twin domains, with LLG scores > roughly reflecting twin ratios. > Similar case is discussed in detail here: > http://www.ncbi.nlm.nih.gov/pubmed/15039553 > >