Hi, We used it in some lysis/refolding buffers.
Sigma marked this biodegradable detergent as "Highly toxic by inhalation" - when it's used in toothpastes and shampoos if I am not mistaken. when I called, Sigma said that since someone published a paper saying that when they sprayed it into a rat's nose the rat died, they had no choice but to put a skull sign on the MSDS. Zhijie From: Rashmi Panigrahi Sent: Thursday, September 20, 2012 5:47 AM To: CCP4BB@JISCMAIL.AC.UK Subject: [ccp4bb] sarkosyl Hi All, I was wondering if anyone has used N-lauryl sarcosine in the lysis buffer for purifying protein and checked if the protein was functional or structurally okay Please let me know kind regards -- rashmi