On Mon, Jan 7, 2013 at 1:28 AM, Xiaopeng Hu <huxp...@mail.sysu.edu.cn> wrote: > We recently resolved an enzyme/inhibitor complex structure. The enzyme > contains two NCS related active site and we did find extra density in both of > them.However we observed that the two inhbitor moleculors are not NCS > related, but partly overlaped if make a NCS moleculor. Has anyone else > observed this before? Thanks for any help and suggestion!
If I'm not misunderstanding the question, some HIV protease inhibitor complexes do this too. PDB ID 2fxe is a good example. -Nat
