Hi
I'd just integrate them individually with Mosflm, then merge the two
MTZ files into one with Pointless(*), then scale with Aimless.
(*)
pointless hklin first.mtz second.mtz hklout pointless.mtz
aimless hklin pointless.mtz hklout aimless.mtz
should do the trick - pointless even works with a wild card if you
have many mtz files to merge (not sure how many "many" can be, but
it's certainly a lot more than 10), e.g.
pointless hklin part_*.mtz hklout pointless.mtz
Dead easy with normal CCP4 programs, RTM for pointless for further
details.
You can even do this in ccp4i *really easily*!
On 28 Mar 2013, at Thu28 Mar 10:08, S. Thiyagarajan wrote:
Dear all
I have two data sets, 75 frames each from crystals of the same
protein - same cell parameters/space group (P4).
I could process them seperately each yielding > 90% completeness
but with poor multiplicity ( < 2 )
If I merge the data sets using CAD, I loose the data reduction
statistics of the combined data set.
I do not have HKL2000.
Which (free) tool can handle two different diffraction data sets,
process them together to give a single final data statistics.
Thanks and regards
Thiyaga
S. Thiyagarajan
Centre of Excellence in Bioinformatics
School of Biotechnology
Madurai Kamaraj University
Madurai - 625021
Ph: +91-9159224881 (cell)
Harry
--
** note change of address **
Dr Harry Powell, MRC Laboratory of Molecular Biology, Francis Crick
Avenue, Cambridge Biomedical Campus, Cambridge, CB2 0QH
Chairman of European Crystallographic Association SIG9
(Crystallographic Computing)