The Institute of Cancer Research (ICR) is one of the world’s most influential 
cancer research institutes. Our mission is to make the discoveries that defeat 
cancer. We have a long and distinguished history of research with a major 
impact on the outcome for cancer patients. Our unique partnership with The 
Royal Marsden NHS Foundation Trust (RMH) makes us the largest comprehensive 
cancer centre in Europe, performing high quality original basic research and 
translational studies. The ICR was ranked as the UK’s top academic research 
centre in the 2008 Higher Education Funding Council Research Assessment 
Exercise. Based on our publication record, citations and impact we rank among 
the world’s leading cancer research centres.
The Cancer Research UK Cancer Therapeutics Unit (CTU), embedded within the 
Division of Cancer Therapeutics, is a multidisciplinary 'bench to bedside' 
centre, comprising around 160 staff dedicated to the discovery and development 
of novel therapeutics for the treatment of cancer. The Cancer Therapeutics 
Unit’s exciting goal is to discover high quality drug candidates for validated 
biological targets and to progress these candidates to clinical trial. All the 
scientific disciplines are in place to make this possible, including medicinal 
chemistry, biology, drug metabolism and clinical specialists.
A postdoctoral position for a protein crystallographer has become available in 
Dr Rob van Montfort’s Hit Discovery and Structure-based Design Team within the 
Cancer Therapeutics Unit (Ref. 1324229) The postdoctoral fellow will be 
involved in the structure determination of one of our cancer targets and 
subsequent high-throughput X-ray crystallography, fragment-based screening and 
structure-based drug design. The successful candidate will interact closely 
with the biology, computational chemistry and medicinal chemistry teams at the 
Cancer Therapeutics Unit as well as with the protein crystallographers in the 
Division of Structural Biology in which the crystallography efforts of Dr van 
Montfort’s team are embedded. Therefore the successful candidate will be 
expected to work across the two sites in Chelsea, London and Sutton, Surrey.
Applicants must have a PhD in a biological or physical science, and experience 
in macromolecular crystallography (to include protein biochemistry, protein 
crystallisation, & protein crystallography). Experience in molecular biology 
and/or structure-based drug design will be an advantage.
The starting salary for the positions will be in the range £28,087 to £38,990 
p.a. inclusive (based on previous post-doctoral experience) and the posts are 
offered on a fixed term contract of 2 years. Informal enquiries to 
rob.vanmontf...@icr.ac.uk<mailto:rob.vanmontf...@icr.ac.uk> or 
isaac.westw...@icr.ac.uk<mailto:isaac.westw...@icr.ac.uk>. Please DO NOT send 
your application to Dr van Montfort or Dr Westwood; applications must be 
submitted in line with the instructions on our website: 
http://www.icr.ac.uk<http://www.icr.ac.uk/>. Closing date April 29th 2013.

Dr. Rob van Montfort
Team Leader Hit Discovery and Structural Design
Sections of Cancer Therapeutics and Structural Biology
The Institute of Cancer Research
15 Cotswold Road
Sutton SM2 5NG
UK

Tel:
+44-(0)20-8722-4364 (Sutton)
+44-(0)20-7153-5142 (Chelsea)
Email: rob.vanmontf...@icr.ac.uk<mailto:rob.vanmontf...@icr.ac.uk>


The Institute of Cancer Research: Royal Cancer Hospital, a charitable Company 
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Registered Office at 123 Old Brompton Road, London SW7 3RP.

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