Re: [ccp4bb] Off-topic: NMR and crystallography

[El Arnaout, Toufic]

Hi Theresa, Here is a comparison between both methods (Table under "6-Summary"): http://www.cryst.bbk.ac.uk/pps97/assignments/projects/ambrus/html.htm If you would like to have an idea about structures of membrane proteins (why was NMR used and what answers they got etc) solved by NMR to date please check: http://www.drorlist.com/nmr/MPNMR.html ; for solid-state NMR: http://www.drorlist.com/nmr/SPNMR.html I'm sure any lab would be happy to solve their structures using both methods (if they can) + publish high impact papers. Even if structural differences exist, why not.. more to discuss :) Sometimes large differences are more related to the detergent/environment or many other factors that affect memb proteins. Regards toufic el arnaout School of Medicine - 660 S Euclid Ave Washington University in St. Louis St Louis, MO 63110 > Date: Sun, 9 Jun 2013 16:36:15 +0100 > From: theresah...@live.com > Subject: [ccp4bb] Off-topic: NMR and crystallography > To: CCP4BB@JISCMAIL.AC.UK > > Dear all > > A question for the cross-trained members of this forum - for small sized proteins, is NMR better than crystallography in terms of data collection (having crystals in the first place) and data processing? How about membrane proteins? > > I would appreciate replies to the board, instead of off-board, to allow for a good discussion. > > Thank you. > > Theresa >