You sure about this space group? 24 monomers in P1 is unusual (at least to me)

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> On Jan 18, 2014, at 9:14 AM, Chris Fage <cdf...@gmail.com> wrote:
> 
> Hello Everyone,
> 
> I am currently trying to phase a structure with an asymmetric unit predicted 
> to contain 20-24 monomers (space group P1). The native crystals, while 
> beautiful in appearance (see attached), only diffract to ~3.4-3.0 angstroms 
> at best, and SeMet-derived crystals grow with poor morphology (small 
> needles). Also, based a fluorescence scan, I know that mercury does not bind 
> appreciably. Other than screening for a new space group, what options might I 
> have for phasing this many monomers at lower resolution? Is there any real 
> chance of solving the structure in this space group?
> 
> Thank you in advance for any suggestions!
> 
> Regards,
> Chris
> <Crystals.jpg>

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