>Burning/frying the crystal is never the right strategy, at least not if you >use a Pilatus detector.
>Burning/frying is a strategy that results from the widespread misunderstanding >of using Rsym >as a criterion of data quality. I apologise if I didn't make myself clear. The point I tried to make is that it is ok to strive to obtain higher resolution with native data sets ... and yes, "fry" is a poor choice of a word on my side as it implies damage to the crystal, which is not what I meant. I simply tried to emphasise that going for high resolution is ok when collecting native data sets but not when collecting anomalous ones. The rest of my message made a point of collecting data with high attenuation and fast shutter speed at a lower resolution to keep the anomalous signal high in as many images as possible before X-ray damage sets in lowers it. Tony ------------------------------------------------------ Antonio Ariza University of Oxford Sir William Dunn School of Pathology South Parks Road Oxford OX1 3RE
