Hi All, We recently obtained a native data set to 2.8A. With no molecular replacement available we are now moving to heavy atom (not enough methionine coverage for seleno-met). Unfortunately crystals grow is in 1.4 Na/K H phosphate pH 8 and we do not have much room for improvement. Any literature you could point to or experience with for example gadolinium complexes, co-crystallization, soaking in phosphate buffer? Are we better off just focusing on class B metals?
Thanks for your advise. Kind Regards, Isa ______________________________________________________________________ The information in this email is confidential and intended solely for the addressee. You must not disclose, forward, print or use it without the permission of the sender. ______________________________________________________________________
