The fact that the PDB holds hundreds of FABs and a handful whole ABs
suggests to me that the latter are hard to get crystals for. So, all the
more reason for us bioinformaticians that you, experimentalists try it :-)
Gert
On 22-6-2017 20:39, Cheng Zhang wrote:
Hi all,
I have a naive question about antibodies. Many people used Fab
fragments in crystallization. I am wondering if it is possible to use
the whole IgG molecule with Fc fragment as well. Or it would be too
flexible and bad for crystallization?
Thanks,
Cheng
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Cheng Zhang
