Pavel, Please correct if wrong, but I thought most refinement programs used the weights e.g. sig(I/F) with I/F so would not really have a hard cut off anyway? You’re just making the stats worse but the model should stay ~ the same (unless you have outliers in there)
Clearly there will be a point where the model stops improving, which is the “true” limit… Cheers Graeme On 5 Jul 2019, at 06:49, Pavel Afonine <pafon...@gmail.com<mailto:pafon...@gmail.com>> wrote: Hi Sam Tang, Sorry for a naive question. Is there any circumstances where one may wish to refine to a lower resolution? For example if one has a dataset processed to 2 A, is there any good reasons for he/she to refine to only, say 2.5 A? yes, certainly. For example, when information content in the data can justify it.. Randy Read can comment on this more! Also instead of a hard cutoff using a smooth weight based attenuation may be even better. AFAIK, no refinement program can do this smartly currently. Pavel ________________________________ To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB&A=1 -- This e-mail and any attachments may contain confidential, copyright and or privileged material, and are for the use of the intended addressee only. If you are not the intended addressee or an authorised recipient of the addressee please notify us of receipt by returning the e-mail and do not use, copy, retain, distribute or disclose the information in or attached to the e-mail. Any opinions expressed within this e-mail are those of the individual and not necessarily of Diamond Light Source Ltd. Diamond Light Source Ltd. cannot guarantee that this e-mail or any attachments are free from viruses and we cannot accept liability for any damage which you may sustain as a result of software viruses which may be transmitted in or with the message. Diamond Light Source Limited (company no. 4375679). Registered in England and Wales with its registered office at Diamond House, Harwell Science and Innovation Campus, Didcot, Oxfordshire, OX11 0DE, United Kingdom ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB&A=1