Hi Rajnandani, I’m happy to help you with questions about moonlighting proteins. My lab created the MoonProt Database (moonlightingproteins.org<http://moonlightingproteins.org>).
I think you’re asking about 2 proteins with a similar fold having similar but not exactly the same functions - yes, that does occur. Best regards, Connie Jeffery On Feb 2, 2020, at 4:28 AM, Rajnandani Kashyap <kashyap.rajnand...@gmail.com<mailto:kashyap.rajnand...@gmail.com>> wrote: Dear All I am curious to know about the promiscuous activity of a protein based on their fold. Can a protein having same fold also have same function (say not 100% but some activity) as the homologous structure. Please also let me know few relevant PDB structures where such kind of activity is shown promising. Regards Rajnandani Kashyap PhD Student ________________________________ To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB&A=1 ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB&A=1