I believe this is more than a fluke. It looks to me like a very powerful evolutionary tool which may have rendered the early stages in the evolution of life less improbable. Best wishes, Emmanuel Saridakis
----- Original Message ----- From: "Peter Stogios" <p.stog...@utoronto.ca> To: "CCP4BB" <CCP4BB@JISCMAIL.AC.UK> Sent: Monday, 3 February, 2020 02:18:45 Subject: Re: [ccp4bb] Protein fold and the moonlighting function I think you’re asking if two proteins with the same fold can have different activities. As was previously mentioned, this is quite common. The best characterized example is the TIM barrel fold - such proteins can be isomerases, transferases, hydrolases, lyases, or oxidoreductases, to name a few... ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB&A=1 ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB&A=1
