Dear all Is anomalous diffraction necessary for determining experimental phases and the Hendrickson-Lattman coefficients (HLA, HLB, HLC, and HLD)?
MR solution from Phaser 2.8.3 (interfaced in ccp4 8.0.000 suite) seems to be generating HLA/B/C/D coefficients from an x-ray diffraction dataset. Wavelength: 1.54179 Angstrom. Sample: 1. Protein-small molecule ligand complex crystal. 2. No anomalous scatterer in the protein, the ligand, or the crystallization condition. Data reduction: Xtriage and aimless analyses did not indicate significant anomalous signal. I would appreciate any help in understanding the reasons for these observations. Thanks and regards Nitin Kulhar PhD student c/o Dr Rajakumara Eerappa Macromolecular Structural Biology Lab Department of Biotechnology Indian Institute of Technology Hyderabad Kandi, Sangareddy Telangana, India - 502284 -- Disclaimer:- This footer text is to convey that this email is sent by one of the users of IITH. So, do not mark it as SPAM. ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1 This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list hosted by www.jiscmail.ac.uk, terms & conditions are available at https://www.jiscmail.ac.uk/policyandsecurity/
